high capacity freeze dryer
Three-quarter right view of a professional laboratory freeze dryer unit on wheels, featuring dual transparent chambers and side connection ports.
Four-quadrant display of lyophilizer applications showing freeze-dried fruits and vegetables, meat cubes, pharmaceuticals with a syringe, and flower tea.
Three-quarter left view of a white pilot-scale vacuum freeze dryer lyophilizer showing its deep cabinet structure and a side ventilation grille.
high capacity freeze dryer

Geliss Large-Capacity Pharmaceutical Vial Freeze Dryer with Automatic Capping

ZLGJ-50FY
Product Details
Place Of Origin: China
Brand Name: Geliss
Certification: CE
Payment & Shipping Terms
Minimum Order Quantity: 1 Unit
Price: Available Upon Request
Packaging Details: Plywood Case
Delivery Time: 7-30 Working Days
Payment Terms: T/T
Supply Ability: 200 Units/Month
Quantity:
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Product Overview

The ZLGJ-50FY is a high-capacity, pilot-scale silicone oil vacuum freeze-dryer equipped with a hydraulic stoppering system. Designed specifically for pilot-scale scale-up, small-batch production, and high-precision aseptic sample processing in the pharmaceutical industry, it ensures the sterility and consistency of vial sealing. The unit features a silicone oil constant-temperature circulation system, dual independent Tecumseh compressor units, and high-pressure defrosting technology; it offers a freeze-drying area of ​​0.5 m² (configured with 3+1 shelf layers), a minimum cold trap temperature of ≤-75°C, and a water-trapping capacity exceeding 8 kg. Manufactured in strict accordance with GMP, FDA, and GB/T5226.1-1996 standards, the equipment utilizes an integrated structural design to ensure operational stability and ease of transport. It is ideally suited for overseas pharmaceutical companies, health supplement manufacturers, and testing institutions, meeting requirements for efficient, compliant, aseptic closed-loop operations and independent dual-compressor refrigeration control.

Key Features

This silicone oil constant-temperature circulation system is equipped with an imported Grundfos canned motor pump, ensuring that—once the system stabilizes—the temperature uniformity across the shelves remains within ±1°C. Under no-load conditions, the system achieves smooth temperature ramping within 60 minutes; by preventing component degradation caused by localized overheating, it gently preserves the activity of heat-sensitive substances (such as proteins and peptides), thereby ensuring consistent product quality across batches.
Infographic card showing a high-resolution MCGS digital touch display screen control panel for a professional laboratory freeze dryer system.
Product feature diagram displaying a clear thick acrylic chamber door with excellent pressure resistance and visibility for a vacuum freeze dryer.
Product feature diagram displaying a clear thick acrylic chamber door with excellent pressure resistance and visibility for a vacuum freeze dryer.

Technical Specifications 

 
    MODELZLGJ-10FDYZLGJ-20FYZLGJ-30FYZLGJ-50FYZLGJ-100FYZLGJ-200FY
    Freeze-dryingarea0.1㎡0.2㎡0.3㎡0.5㎡1㎡2.1㎡
    Temperature scope of shelf-50℃-+70℃(no-load)-50℃-+70℃(no-load)-50℃-+70℃(no-load)-50℃-+70℃(no-load)-50℃-+70℃(no-load)-50℃-+70℃(no-load)
    shelf temperatureerror±1℃(in balance)±1℃(in balance)±1℃(in balance)±1℃(in balance)±1℃(in balance)±1℃(in balance)
    Min. Temperature of condenser≤-60℃(no-load)≤-75℃(no-load)≤-75℃(no-load)≤-75℃(no-load)≤-75℃(no-load)≤-75℃(no-load)
    Water-capture capability＞2Kg＞4Kg5Kg＞8Kg＞20Kg＞30Kg
    final Vacuum degree≤ 10Pa≤ 10Pa≤ 10Pa≤ 10Pa≤ 10Pa≤ 10Pa
    Layers of shelf1（Shelf spacing）100 mm2（Shelf spacing）100 mm3（Shelf spacing）100 mm3（Shelf spacing）100 mm4（Shelf spacing）100 mm4（Shelf spacing）100 mm
    PowerSingle phase 220VSingle phase 220V or three-phase 380VSingle phase 220V or three-phase 380VSingle phase 220V or three-phase 380V tSingle phase 220V or three-phase 380Vthree-phase 380V
    Installed power1.5KW (this is installed power, not running power)2.8 KW (this is installed power, not running power)3.5 KW (this is installed power, not running power)6.5 KW (this is installed power, not running power)7.5 KW (this is installed power, not running power)12.5 KW (this is installed power, not running power)
    Whole machine sizeAbout 780x650x1210mmAbout 800x800x1650mmAbout 950x1240x1450mmAbout 980x1570x1970mmAbout 1150x1580x1980mmAbout 1150x1580x1980mm
    Whole machine weight (kg)About 220About 323About 320About 800About 1300About 1300
     

    Application Fields

    This equipment is suitable for pilot-scale and small-batch production in pharmaceutical companies, R&D in biological laboratories, high-end health supplement manufacturing, as well as precision testing and quality control. It enables small-batch, aseptic freeze-drying of products such as injectable drugs, active pharmaceutical ingredients (APIs), antibodies, diagnostic reagents, peptides, probiotics, and active ingredients, while preserving the materials' original nutritional value and biological activity.

    Three-quarter left view real shot of a white vertical pilot vacuum freeze dryer unit inside a manufacturing workshop, showing its deep side panel and mesh vent.
    Straight front view real shot of a pilot freeze dryer lyophilizer machine, showcasing its upper square drying chamber, integrated touch screen, and round lower cold trap.
    Three-quarter right view real shot of a commercial laboratory freeze dryer machine on wheels, highlighting the robust door latches and side cooling ventilation layout.

     

    Frequently Asked Questions 

    Q: What are the advantages of hydraulic stoppering compared to manual mechanical stoppering?
    A: The hydraulic system ensures uniform and repeatable stoppering force across the entire shelf. This high-capacity freeze dryer applies a uniform pressure of approximately 1.0 kg/cm², ensuring consistent sealing for every vial while eliminating issues caused by operator fatigue or inconsistent handling.
    Q: Can this pharmaceutical-grade freeze dryer operate without a water-cooling system?
    A: Yes. The unit utilizes a dual-compressor air-cooled system that dissipates heat directly into the air, requiring only a well-ventilated environment. It is ideal for production facilities that lack chilled water piping infrastructure.
    Q: How many 2ml vials can be processed per batch?
    A: It can process 3,538 vials per batch. This offers true large-scale freeze-drying capability, making it perfect for the transition from pilot scale to full-scale production.
    Q: Is the silicone oil circulation system safe for injectable products?
    A: It is completely safe. The circulation loop is fully sealed and does not come into contact with the product. The system uses low-viscosity, food-grade silicone oil, posing no risk of contamination.
    Q: What validation documentation is provided with the equipment?
    A: The documentation includes material certificates, welding records, surface roughness reports, IQ/OQ (Installation Qualification/Operational Qualification) protocols, and calibration certificates. We fully support you in meeting GMP and FDA compliance requirements.

    Call to Action

    Contact us today for a customized solution and a detailed quote for the ZLGJ-50FY model! You will also receive a technical manual on the silicone oil constant-temperature circulation system and a GMP compliance validation package, helping you optimize pilot-scale production and aseptic stoppering processes while ensuring stable, efficient, and regulatory-compliant vacuum freeze-drying operations.

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