Geliss Hydraulic GMP Pilot-Scale Freeze Dryer with Silicone Oil Heating and Stoppering Function
Place Of Origin: China
Brand Name: Geliss
Certification: CE
Payment & Shipping Terms
Minimum Order Quantity: 1 Unit
Price: Available Upon Request
Packaging Details: Plywood Case
Delivery Time: 7-30 Working Days
Payment Terms: T/T
Supply Ability: 200 Units/Month
Product Introduction
The ZLGJ-30FY is a silicone oil-heated vacuum freeze-dryer designed for pilot-scale and small-batch pharmaceutical production; it features a manual hydraulic stoppering system that ensures consistency and sterility during the sealing process. The unit utilizes a closed-loop silicone oil heat transfer system and a high-pressure defrosting system. Key technical specifications include a freeze-drying area of 0.3 m², a"3+1"shelf configuration, a minimum cold trap temperature of ≤-75°C, and a water-trapping capacity exceeding 5 kg. Compliant with GMP and GB/T5226.1-1996 standards, the equipment is characterized by its compact structure and stable operation, making it an ideal choice for overseas laboratories, pharmaceutical companies, and testing institutions to conduct reliable scale-up freeze-drying and in-situ stoppering processes.
Core Advantages
This manual hydraulic stoppering system applies uniform pressure of approximately 1.0 kg/cm², ensuring a reliable seal in a single operation; its in-situ stoppering capability eliminates the risk of cross-contamination, perfectly meeting the clean production requirements for vials in pharmaceutical R&D and batch manufacturing. Equipped with dual independent Tecumseh compressors and air cooling, the system operates stably without the need for water cooling; independent refrigeration controls for the shelves and cold trap ensure consistent, long-term performance, making it an ideal choice for laboratories and small-scale production facilities in water-scarce regions.



Technical Specifications
| MODEL | ZLGJ-10FDY | ZLGJ-20FY | ZLGJ-30FY | ZLGJ-50FY | ZLGJ-100FY | ZLGJ-200FY |
| Freeze-dryingarea | 0.1㎡ | 0.2㎡ | 0.3㎡ | 0.5㎡ | 1㎡ | 2.1㎡ |
| Temperature scope of shelf | -50℃-+70℃(no-load) | -50℃-+70℃(no-load) | -50℃-+70℃(no-load) | -50℃-+70℃(no-load) | -50℃-+70℃(no-load) | -50℃-+70℃(no-load) |
| shelf temperatureerror | ±1℃(in balance) | ±1℃(in balance) | ±1℃(in balance) | ±1℃(in balance) | ±1℃(in balance) | ±1℃(in balance) |
| Min. Temperature of condenser | ≤-60℃(no-load) | ≤-75℃(no-load) | ≤-75℃(no-load) | ≤-75℃(no-load) | ≤-75℃(no-load) | ≤-75℃(no-load) |
| Water-capture capability | >2Kg | >4Kg | 5Kg | >8Kg | >20Kg | >30Kg |
| final Vacuum degree | ≤ 10Pa | ≤ 10Pa | ≤ 10Pa | ≤ 10Pa | ≤ 10Pa | ≤ 10Pa |
| Layers of shelf | 1(Shelf spacing)100 mm | 2(Shelf spacing)100 mm | 3(Shelf spacing)100 mm | 3(Shelf spacing)100 mm | 4(Shelf spacing)100 mm | 4(Shelf spacing)100 mm |
| Power | Single phase 220V | Single phase 220V or three-phase 380V | Single phase 220V or three-phase 380V | Single phase 220V or three-phase 380V | tSingle phase 220V or three-phase 380V | three-phase 380V |
| Installed power | 1.5KW (this is installed power, not running power) | 2.8 KW (this is installed power, not running power) | 3.5 KW (this is installed power, not running power) | 6.5 KW (this is installed power, not running power) | 7.5 KW (this is installed power, not running power) | 12.5 KW (this is installed power, not running power) |
| Whole machine size | About 780x650x1210mm | About 800x800x1650mm | About 950x1240x1450mm | About 980x1570x1970mm | About 1150x1580x1980mm | About 1150x1580x1980mm |
| Whole machine weight (kg) | About 220 | About 323 | About 320 | About 800 | About 1300 | About 1300 |
Application Fields
The ZLGJ-30FY pilot-scale freeze dryer, featuring a vial-stoppering function, is designed specifically for pharmaceutical enterprises to conduct process validation and pilot production of injectable freeze-dried drugs and biological products. With precise silicone oil temperature control and pilot-scale batch processing capabilities, the equipment provides reliable data to support full-scale mass production. Tailored for the small-batch production of injectable freeze-dried drugs, antibodies, and protein formulations, the system ensures product sterility and production efficiency through precise manual stoppering and high-pressure, high-efficiency defrosting technologies. In the premium health supplement sector, it supports the small-batch production of high-quality products such as freeze-dried peptides and probiotics; its precise silicone oil temperature control effectively preserves the natural nutrients and biological activity of the materials, thereby meeting the industry's rigorous quality standards.



Frequently Asked Questions
A: For pilot-scale applications, manual stoppering offers greater flexibility when handling vials of various specifications.
Q: Is this silicone oil-heated freeze dryer suitable for highly active pharmaceutical ingredients (APIs)?
A: Yes, it is. The unit utilizes a closed-loop system to effectively prevent cross-contamination. All internal surfaces are made of electropolished stainless steel, making them easy to clean.
Q: What validation documentation is included with the equipment?
A: This GMP-compliant freeze dryer comes with material certificates, welding records, surface roughness reports, IQ/OQ (Installation Qualification/Operational Qualification) protocols, and calibration certificates.
Q: Does the equipment include a vacuum pump?
A: Yes. It comes standard with a Yonghao two-stage rotary vane pump. You also have the option to upgrade to an oil-free pump or a pump with a higher pumping speed to reduce evacuation time.
Q: How long does high-pressure defrosting take?
A: Typically 10 to 15 minutes, depending on the amount of ice buildup. In contrast, natural defrosting can take 2 to 3 hours. This feature alone can increase your daily processing capacity by 30%.
Call to Action
Ready to scale up your freeze-drying process to the pilot level with full GMP documentation? Contact us today for a customized quote and a free product brochure for this pilot-scale freeze dryer. We will assist you in selecting the optimal shelf configuration and vial layout while providing comprehensive validation support—delivering practical, expert advice rather than empty talk.
📦 Bulk & Custom Orders: Special pricing available for pharmaceutical companies, CROs, and research institutions.
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